In being born, Christ made the former entranceway of sin into a portal of salvation. For, in the place where the serpent had injected its venom through disobedience, the Word, entering by his obedience, built a living temple. Whence had emerged Cain, the firstborn of sin, thence without seed sprang Christ, the Redeemer of the human race
Proclus of Constantinople, Homily 1, 2; PG 65, 681 C.
In another homily, he adds that the effects of Mary’s collaboration in the economy of salvation extend to all the dimensions of the world:
You alone cured Eve’s sorrow; you alone wiped away the tears of travail; you alone bore the world’s ransom.
Proclus of Constantinople, Homily s, 3; PG 65, 720 C.
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References:
Gambero, L., 1999. Mary and the Fathers of the Church 1st ed. Translated by Buffer, T., San Francisco: Ignatius Press.
Virgin Mary 
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